Secondary metabolites from the tubers of Dioscorea persimilis

Abstract

Seven secondary metabolites were isolated from the aqueous fraction of Dioscorea persimilis tubers using combined chromatographic techniques. Their structures were identified as 4-0-(6'-O-glucosyl-4"-hydroxybenzoyl)-4- hydroxybenzyl alcohol (1), trans-N-p-coumaroyltyramine (2), cyclo-(Phe-Tyr) (3), syringaresinol (4), syringaresinol O- β-D-glucopyranoside (5), corchoionoside C (6), and oct-1-en-3-yl arabinopyranosyl-(1-6)-β-glucopyranoside (7) by ID and 2D NMR and MS methods in comparison with the data reported in the literature. In addition, weak eytotoxicity on HepG2, MCF7, and SK-Mel-2 cancer cell lines were observed for compounds 1-3. Notably, this is the first time to report the isolation, structural elucidation, and cytotoxicity of compound 1.