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DC Field | Value | Language |
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dc.contributor.author | Nguyen, Thi Dung | - |
dc.contributor.author | Pham, Thi Ninh | - |
dc.contributor.author | Nguyen, Thi Luu | - |
dc.contributor.author | Nguyen, The Anh | - |
dc.contributor.author | Vu, Thi Bich Hau | - |
dc.contributor.author | Nguyen, Thi Thu Thuy | - |
dc.contributor.author | Ho, Ngọc Anh | - |
dc.contributor.author | Phan, Dieu Hang | - |
dc.contributor.author | Tran, Thi Phuong Thao | - |
dc.date.accessioned | 2024-06-27T07:09:09Z | - |
dc.date.available | 2024-06-27T07:09:09Z | - |
dc.date.issued | 2023 | - |
dc.identifier.issn | 2525-2321 | - |
dc.identifier.uri | https://dspace.ctu.edu.vn/jspui/handle/123456789/103989 | - |
dc.description.abstract | The ethanol extract from the leaves and twigs of Euphorbia cyathophora showed antiviral activity against four dengue virus serotypes (DENV1-4), with PRNT₅₀ values of 15.625-62.5 µg/mL. Eight compounds including germanicol acetate (1), cymbopogone (2), 1-heptacosanol (3), ethyl α-L-arabinofuranoside (4), quercetin (5), 3-acetoxy-5,7,3',4'- tetrahydroxyflavone (6), 3-acetoxy-5,7,4-trihydroxyflavone (7), 4'-acetoxy-3,5,7-trihydroxyflavone (8) were isolated from this extract. Compounds 2-8 were isolated for the first time from Euphorbia cyathophora. Antiviral activity evaluation of compounds 1-3, 5-7 on DENV1-4 serotypes revealed that 7 was the most active compound with PRNT₅₀ values of 23.8-95.2 μΜ. | vi_VN |
dc.language.iso | en | vi_VN |
dc.relation.ispartofseries | Vietnam journal of Chemistry;Vol.61, No.03 .- P.371-377 | - |
dc.subject | Euphorbia cyathophora | vi_VN |
dc.subject | Antidengue activity | vi_VN |
dc.subject | Secondary metabolites | vi_VN |
dc.title | Phytochemical study of Euphorbia cyathophora collected in Dan Phuong, Hanoi and its antidengue activity against DENV1-4 virus serotypes | vi_VN |
dc.type | Article | vi_VN |
Appears in Collections: | Vietnam Journal of Chemistry |
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