Electrochemical determination of salbutamol in aqueous solutions with UiO-66/rGO-modified electrodes

Abstract

The synthesis of the UiO-66/rGO material involved combining UiO-66 with reduced graphene oxide (rGO). This resulting composite found application in the electrochemical determination of salbutamol (SAL) through modification of a glassy carbon electrode (GCE) with UIO-66/rGO. Differential pulse voltammetry served as the chosen technique, offering a wide linear range spanning 1-160 µм and demonstrating a low limit of detection at 0.84 μμ. Το ensure the reliability of the electrode, various aspects such as sensitivity, repeatability, reproducibility, and stability were meticulously studied. When applied to the analysis of SAL in swine urine solutions (n=3), the electrode exhibited good recovery rates. Remarkably, the results obtained through this method correlated well with those acquired using ultra high performance liquid chromatography (UPLC).