Acetylcholinsterase inhibitory activity and flavonoid from Rosa canina L.

Abstract

From fruit of Rosa canina L. (R. canina), an isoflavonoid: Dalbergioidin (1) was isolated. The structure of this compound was characterized on the basis of IR, NMR spectroscopic techniques. Furthermore, anti-acetylcholinesterase action of the extracts were examined. The results showed that methanol extract from fruit of R. canina had weak acetylcholinesterase inhibitory activity with IC₅₀ 93.96µg/ml.