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https://dspace.ctu.edu.vn/jspui/handle/123456789/21859| Title: | Synthesis and biological activities of organoaluminum steroids |
| Authors: | Dzhemilev, Usein M. D’yakonov, Vladimir A. Tuktarova, Regina A. Gloriozova, Tatyana A. Dzhemileval, Lilya U. Terent’ev, Alexander O. Dembitsky, Valery M. |
| Keywords: | Synthesis Organoaiuminum Cycloalumination Steroids Antiprotozoal Anti-hyperdiolesterolemic Activity |
| Issue Date: | 2018 |
| Series/Report no.: | Vietnam Journal of Chemistry;No 56(06) .- Page.661-666 |
| Abstract: | This review presents the synthesis of organoaluminum steroids (OAS) using catalytic cycloalumination of vinylcholestane and/or allycholestane derivatives with Et₃Al catalyzed by Cp₂ZrCl₂ which gives aluminacyelopentanes in a yield of about 90 %. Biological activity of synthesized organoaluminum steroids was determined with an aid of PASS program. Organoaluminum steroids showed antiprotozoal, antihypercholesterolemic, and antieczematic activity with a certainty from 78 to 92 %. |
| URI: | http://dspace.ctu.edu.vn/jspui/handle/123456789/21859 |
| ISSN: | 2525-2321 |
| Appears in Collections: | Vietnam Journal of Chemistry |
Files in This Item:
| File | Description | Size | Format | |
|---|---|---|---|---|
| _file_ Restricted Access | 3.65 MB | Adobe PDF | ||
| Your IP: 18.219.150.195 |
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