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Title: | Antiproliferative activity of isolated compounds from Pinus dalatensis and Pinus krempfii on acute myeloid Leukemia cells |
Authors: | Nguyen, Hoang Sa Nguyen, Thanh Tam Tran, Duc Quan Nguyen, Thi Hoang Anh Nguyen, Thi Thuy Linh Le, Thi Hong Nhung Adorisio Sahrina Delfino, Domenico V Tran, Van Sung Trinh, Thi Thuy |
Keywords: | Pinus dalatensis Pinus krempfìi Chrysin Acute mycloid leukemia (OCI-ALM) |
Issue Date: | 2019 |
Series/Report no.: | Vietnam Journal of Chemistry;№ 57(04) .- Page.520-523 |
Abstract: | Our previous chemical constituent study of Pinuts dalatensis and Pinus krempfìi had identified six compounds 1-6. The continuing investigation of biological activity of the conifer species led to discovery of the antiproliferative activity of all isolated compounds 1-6 on acute myeloid leukemia cells as shown by the effects on cell cycle progression. Re-markably, compound 3 (chrysin) exibited potent bioactivity at the concentration of 10 µg-mL. |
URI: | http://dspace.ctu.edu.vn/jspui/handle/123456789/23343 |
ISSN: | 2525-2321 |
Appears in Collections: | Vietnam Journal of Chemistry |
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Your IP: 18.218.63.176 |
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