Development of the generation of alkyl radicals from N-tosyloxaziridines

Abstract

Oxaziridines have attracted much interest of chemists for decades as effective electroscopic oxygen and nitrogen sources. The radical chemistry of oxaziridines is quite rare. We, herein, introduce a novel protocol for successful generation of alkyl radicals from N-tosyloxaziridines. These radicals were trapped by various 1,1-diarylethylenes affording products in moderate to good yields. This investigation is hoped to open up the frontier of oxaziridines' chemistry.