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Title: | Ethanol extract of male Carica papaya flowers demonstrated non-toxic against MCF-7, HEP-G2, HELA, NCI-H460 cancer cell lines |
Authors: | Vo, Thi Nga Nguyen, Thi Hanh Trang Nguyen, Thi Anh Tuyet Nguyen, Kim Phi Phung Ngo, Thi Thuy Duong Nguyen, Thi Hoai Thu |
Keywords: | Carica papaya L Male and female plant Papaya Cancer cell line inhibition |
Issue Date: | 2020 |
Series/Report no.: | Vietnam Journal of Chemistry;Số 58(01) .- Tr.86-91 |
Abstract: | Previous studies showed that some extracts of Carica papaya L. could inhibit various cancer cell lines. In this study, from the flowers and petioles of male Carica papaya L. we report the isolation and structural elucidation of six known compounds including stigmast-4-ene-3-one (1), β-sitosterol 3-0-β-D-glucopyranoside (2), 3-0-(6-0-tetradecanoyl-β-D-glucopyranosyl)-β-sitosterol (3), benzyl β-D-glucopyranoside (4), uracil (5) and palmitic acid (6). Among them, compounds 1, 3, 5 were isolated from C. papaya for the first time. The ethanol extracts of leave, flower and root of male and female papaya and compounds 1.4, 5 were tested for the inhibition of four cancer cell lines including MCF-7, Hep-G2. HeLa, NCI-H460 and all of them were inactive. |
URI: | http://dspace.ctu.edu.vn/jspui/handle/123456789/25636 |
ISSN: | 2525-2321 |
Appears in Collections: | Vietnam Journal of Chemistry |
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Your IP: 18.191.178.145 |
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