Please use this identifier to cite or link to this item: https://dspace.ctu.edu.vn/jspui/handle/123456789/28318
Title: Optimization of l-asparaginase production from escherichia coli using response surface methodology
Authors: Nguyen, Thi Hien Trang
Le, Thanh Hoang
Do, Thi Tuyet
Keywords: Echerichia coli BL21(DE3)
K562
L-asparaginase
MALDI-TOF
Response surface
Issue Date: 2018
Series/Report no.: Journal of Biotechnology;№ 16(04) .- Page.767-775
Abstract: Among the anti tumor drugs, bacterial enzyme L-asparaginase has been employed as the most effective chemotherapeutic agent in pediatric oncotherapy especially for acute lymphoblastic leukemia. In previous study, the L-asparaginase from Erwinia chrysanthermy was expressed in Escherichia coli BL.21(DE3). The recombinant L-asparaginase was produced from recombinant E.coli BL21(DE3) under different cultivation conditions (inducer concentration, inoculum concentration and KH₂PO₄ concentration).
URI: http://dspace.ctu.edu.vn/jspui/handle/123456789/28318
ISSN: 1811-4989
Appears in Collections:Công nghệ sinh học

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