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https://dspace.ctu.edu.vn/jspui/handle/123456789/28733
Title: | Role of NPHS2 gene variants IN steroid response and edema level of Vietnamese pediatric patients with primary nephrotic syndrome |
Authors: | Vu, Thi Thom Pham, Van Dem Vu, Van Nga Pham, Thi Hong Nhung Nguyên, Thi Quynh Huong Doan, Dinh Long |
Keywords: | NPHS2 Pediatric nephrotic syndrome patients Sterotd-resistant nephrotic syndrome Steroid-sensitive nephrotic syndrome |
Issue Date: | 2019 |
Series/Report no.: | Journal of Biotechnology;No 17(02) .- Page.231-237 |
Abstract: | Nephrotic syndrome in children is traditionally classified according to the standard steroid treatment response, and in Vietnamese children about 12.4% of cases are steroid resistant. Currently, more than 24 genes have been associated with nephrotic syndrome in children, with three, NPHS1, NPHS2 and WT1, having a major impact on steroid resistant nephrotic syndrome. This study aims to investigate NPHS2 variants in different nephrotic syndrome groups defined as steroid sensitive nephrotic syndrome (SSNS), steroid resistant nephrotic syndrome (SRNS). |
URI: | http://dspace.ctu.edu.vn/jspui/handle/123456789/28733 |
ISSN: | 1811-4989 |
Appears in Collections: | Công nghệ sinh học |
Files in This Item:
File | Description | Size | Format | |
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_file_ Restricted Access | 1.93 MB | Adobe PDF | ||
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