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https://dspace.ctu.edu.vn/jspui/handle/123456789/31937
Title: | Identification of CYP2C9, VKORC1 genotypes and recommendation of warfarin dose for Vietnamese cardiovascular patients |
Authors: | Nguyen, Dang Ton Nguyen, Thị Thanh Hoa Nguyen, Phan Anh Vu, Phuong Nhung Le, Thi Bich Thao Nguyen, Hai Ha |
Keywords: | Warfarin Pharmacogenetics CYP2C9 gene VKORC1 gene PCR-RFLP |
Issue Date: | 2019 |
Series/Report no.: | Journal of Biotechnology;№ 17(04) .- Page.589-594 |
Abstract: | Warfarin is a well-known anticoagulant that capable of reducing the activity of vitamin K-dependent clotting factors. lt has been widely used for cardiovascular patients. However, patient's genotypes of CYP2C9 and VKORC1 remarkably affects the metabolism of warfarin. This study aims to identily the CYP2C9 and VKORC1 genotypes of 96 Vietnamese patients suffering cardiodynia or myocardial infarction and establish their daily warfarin dose. |
URI: | https://dspace.ctu.edu.vn/jspui/handle/123456789/31937 |
ISSN: | 1811-4989 |
Appears in Collections: | Công nghệ sinh học |
Files in This Item:
File | Description | Size | Format | |
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_file_ Restricted Access | 1.74 MB | Adobe PDF | ||
Your IP: 3.12.34.253 |
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