Mini Review: Anticancer activity of diterpenoid peroxides

Abstract

In this review, we present about 100 diterpenoid hydro- and endoperoxides isolated from algae, liverworts, leaves, bark, roots and other parts of plants. for the vast majority of hydroperoxides, antitumor activity dominates with a confidence of 63 % to 94 %. And for individual hydroperoxides, antiprotozoal (Plasmodium) activity was also found. For endoperoxides, antitumor activity is dominant with a confidence of 59 to 90 percent. Anti-inflammatory, antibacterial and antifungal activities have also been detected for individual endoperoxides. The data obtained are of interest to pharmacologists, medical professionals, as well as to the pharmaceutical industry.