Please use this identifier to cite or link to this item: https://dspace.ctu.edu.vn/jspui/handle/123456789/41283
Title: Volatile compounds and biological activities of essential oil of Globba pendula rhizomes collected at An Giang province
Authors: Ngo, Thi Phuong
Dinh, Thi Thu Thu Thuy
Do, Thi Thao
Do, Thi Thanh Huyen
Le, Ngoc Hung
Nguyen, The Anh
Le, Minh Ha
Keywords: Cytotoxic activity
Globba pendula
NO inhibitory activity
Essential oil
GC-MS
Issue Date: 2020
Series/Report no.: Vietnam Journal of Science and Technology;Vol. 58, No. 04 .- P.434-441
Abstract: The present paper describes chemical composition, NO inhibitory activity against lipopolysaccharide (LPS)-induced nitric oxide release, cytotoxic activity against MCF7 and Hep3B cell lines of the essential oil of Globba pendula Roxb. rhizomes. A total of 25 components of the essential oil were identified by using gas chromatography–mass spectrometry (GC-MS), accounting for 89.55 % of the total oil. δ-selinen (36.45 %) and ishwarane (10.76 %) were the main components. The essential oil was found to possess moderate NO inhibitory effect with IC₅₀ of 41.68 ± 4.51 µg/ml, and significant cytotoxic activity against MCF7 and Hep3B cell lines with IC₅₀ of 28.15 ± 1.08 and 35.24 ± 0.06 µg/ml, respectively. This is the first report on volatile compounds and biological activities of the essential oil of Globba pendula Roxb.rhizomes collected in An Giang province, Viet Nam.
URI: https://dspace.ctu.edu.vn/jspui/handle/123456789/41283
ISSN: 2525-2518
Appears in Collections:Vietnam journal of science and technology

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