Angiotensin-converting enzyme inhibitory and antibacterial activities of low molecular weight peptides derived from spent brewer’s yeast

Abstract

According to the World Health Organization (WHO), hypertension is one of the most common chronic diseases. Cardiovascular disease causes 17.5 million deaths each year, in which hypertension is a direct cause to the death of up to 40%. This hypertension is caused by angiotensin-converting enzyme (ACE). ACE inhibitors consider as an effective therapy in hypertension treatment. Many ACE inhibitors are synthesized by Chemical pathways to control high blood pressure. however, these drugs often cause side effects. Therefore, in the last two decades, many authors have been interested in studying and producing a variety of ACE inhibitory peptides, which are naturally derived (plants, animals, and microorganisms) that help reduces blood pressure and less cause side effects.