Phenolic constituents from the stem barks of rhizophora apiculata blume

Abstract

Using various chromatographic separations, sevenphenolic derivatives (1-7) were isolated from a methanolic extract ofthestem barks of Rhizophora apiculata Blume. Their structures were elucidated to be dunnianoside E (1),(+)-dihydroquercetin (2), 2,6-dimethoxy-[1,4] benzoquinone (3), 2,4,6-trimethoxyphenol (4), 3,4,5-trimethoxybenzyl alcohol (5), hydroxytyrosol (6), and methyl 3,4-dihydroxycinnamate (7)by adetailed analysis via spectroscopic techniques (1D-, 2D-NMR,and ESI-MS data) as well as comparison with those previously reported. This is the first report of compounds 1 and 4-7 from the Rhizophora genus.