Tổng hợp và thử tác dụng ức chế enzym glutaminyl cyclase của một số dẫn chất N-(4-methoxy-3-aminoalkyloxy- phenyl) thiourea mói

Please use this identifier to cite or link to this item: https://dspace.ctu.edu.vn/jspui/handle/123456789/54621

Full metadata record

DC Field	Value	Language
dc.contributor.author	Trần, Phương Thảo	-
dc.contributor.author	Hoàng, Văn Hải	-
dc.date.accessioned	2021-06-09T02:52:17Z	-
dc.date.available	2021-06-09T02:52:17Z	-
dc.date.issued	2018	-
dc.identifier.issn	0866-7861	-
dc.identifier.uri	https://dspace.ctu.edu.vn/jspui/handle/123456789/54621	-
dc.description.abstract	A new series of N-(4-methoxy-3-aminoalkyloxy-phenyl)thiourea were synthesized and their glutaminyl cyclase (QC) inhibitivity was fluorometrically evaluated The compounds were obtained via 6 or 7 steps by well-known reactions. Of these synthesized compounds, four (22-25) showed potential inhibitory activity on glutaminyl cyclase (QC) (ICX values of 9,026.8 nM).	vi_VN
dc.language.iso	vi	vi_VN
dc.relation.ispartofseries	Tạp chí Dược học;Số 509 .- Tr.33-36,87	-
dc.subject	N-(4-Methoxy-3-aminoalkyloxy-phenyl)thiourea	vi_VN
dc.subject	Thiourea	vi_VN
dc.subject	Inhibition	vi_VN
dc.subject	Glutaminyl cyclase	vi_VN
dc.title	Tổng hợp và thử tác dụng ức chế enzym glutaminyl cyclase của một số dẫn chất N-(4-methoxy-3-aminoalkyloxy- phenyl) thiourea mói	vi_VN
dc.type	Article	vi_VN
Appears in Collections:	Dược học

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