Please use this identifier to cite or link to this item: https://dspace.ctu.edu.vn/jspui/handle/123456789/54628
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dc.contributor.authorNguyễn, Đăng Khoa-
dc.contributor.authorNguyễn, Đức Hạnh-
dc.contributor.authorVõ, Thanh Hóa-
dc.contributor.authorĐỗ, Quang Dương-
dc.contributor.authorĐỗ, Đức Minh-
dc.contributor.authorHuỳnh, Thanh Tuấn-
dc.date.accessioned2021-06-09T03:15:21Z-
dc.date.available2021-06-09T03:15:21Z-
dc.date.issued2018-
dc.identifier.issn0866-7861-
dc.identifier.urihttps://dspace.ctu.edu.vn/jspui/handle/123456789/54628-
dc.description.abstractZedoarondiol, known as a sesquiterpene lactone compound of anti-inflammatory activity and inhibitivity on platelet-derived growth factor-induced vascular smooth muscle cells, was extracted from Curcuma aromatica Salisb. Ten experiments were designed by Design-Expert 6.0.6 software to investigate the effects of three independent variables (extraction times, solvent/ material ratio, ethanol concentration) on two dependent variables (the yield of raw extracts and that of zedoarondiol). The cause-effect relations between the independent and dependent variables were investigated. All three independent variables (extraction times, solvent/material ratio and ethanol concentration) were found to affect both above-mentioned dependent variables. The extraction was optimized by BCPharSoft OPT software as: Solvent - ethanol 10%, times of extraction - 3; raho of material/solvent -1/9 (m/v). Zedoarondiol content was determined by the following validated HPLC method: Column - C18; Detector-258 nm; Injection sampe - 20 mL.vi_VN
dc.language.isovivi_VN
dc.relation.ispartofseriesTạp chí Dược học;Số 509 .- Tr.45-48,86-
dc.subjectZedoarondiolvi_VN
dc.subjectCurcuma aromaticavi_VN
dc.subjectExtraction processvi_VN
dc.subjectCause-effect relationsvi_VN
dc.subjectOptimizationvi_VN
dc.titleNghiên cứu mối liên quan nhân quả và tối ưu hóa quy trình chiết xuất dược liệu ngải trắngvi_VN
dc.typeArticlevi_VN
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