Please use this identifier to cite or link to this item:
https://dspace.ctu.edu.vn/jspui/handle/123456789/54645
Full metadata record
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Trần, Thị Nguyên Đăng | - |
dc.contributor.author | Trần, Lê Tuyết Châu | - |
dc.contributor.author | Trần, Phi Hoàng Yến | - |
dc.date.accessioned | 2021-06-09T07:07:32Z | - |
dc.date.available | 2021-06-09T07:07:32Z | - |
dc.date.issued | 2018 | - |
dc.identifier.issn | 0866-7861 | - |
dc.identifier.uri | https://dspace.ctu.edu.vn/jspui/handle/123456789/54645 | - |
dc.description.abstract | With regard the natural triterpenoids of Lingzhi (Ganoderma lucidum (Leyss. ex Fr.) Karst.) that are known as active principles for treatment of dementia-related diseases such as Alzheimer, but of poor absorbility due their hydrophobic nature, nanodispersion dosage forms of the triterpenoid-rich extracts from the Red Lingzhi of Vietnam (NPs-L) were formulated to enhance the cellular uptake of triterpenoids. The obtained products were charaterized. The particle size averaged at ca. 143.940 ± 2.525 nm; the stability derirable for at least 6 months of storage at 30 ± 2 cC and ambient relative humidity of 75% ± 5%; the inhibitory activity on cholinesterase was demonstrated by Ellman method, reaching 50% at 0.094 pg/mL (IC₅₀ = 0.094 pg/mL), as 2.59 times higher than the initial Lingzhi extracts (IC₅₀ = 0.244 pg/mL). | vi_VN |
dc.language.iso | vi | vi_VN |
dc.relation.ispartofseries | Tạp chí Dược học;Số 509 .- Tr.76-79 | - |
dc.subject | Ganoderma lucidum | vi_VN |
dc.subject | AQcid ganoderic A | vi_VN |
dc.subject | Nanoparticle | vi_VN |
dc.subject | Alzheimer | vi_VN |
dc.title | Điều chế hệ tiểu phân nano chứa cao linh chi (Ganoderma lucidum (Leyss. ex Fr.) Karst.) hướng tác dụng kháng cholinestcrase | vi_VN |
dc.type | Article | vi_VN |
Appears in Collections: | Dược học |
Files in This Item:
File | Description | Size | Format | |
---|---|---|---|---|
_file_ Restricted Access | 3.26 MB | Adobe PDF | ||
Your IP: 52.14.223.136 |
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.