Please use this identifier to cite or link to this item: https://dspace.ctu.edu.vn/jspui/handle/123456789/54649
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dc.contributor.authorCao, Thị Cẩm Nhung-
dc.contributor.authorLê, Công Trực-
dc.contributor.authorCao, Việt Phương-
dc.contributor.authorTrần, Phương Thảo-
dc.contributor.authorNguyễn, Hải Nam-
dc.date.accessioned2021-06-09T07:23:36Z-
dc.date.available2021-06-09T07:23:36Z-
dc.date.issued2018-
dc.identifier.issn0866-7861-
dc.identifier.urihttps://dspace.ctu.edu.vn/jspui/handle/123456789/54649-
dc.description.abstract5 novel procaspase-3 activating acylhydrazones synthesized incorporating 4(3H)-quinazolinones (Va-ej and biologically tested for cytotoxicity. These all 5 synthesized compounds exhibited significant cytotoxicity against the foilwing three human cancer cell lines: SW620, colon cancer; PC-3, prostate cancer; NCI-H23, lung cancer. Of them, the most potent compound Vb displayed the highest cytotoxicity, as up to 4-fold as potent than 5-FU (5-fluorouracil).vi_VN
dc.language.isovivi_VN
dc.relation.ispartofseriesTạp chí Dược học;Số 510 .- Tr.3-7-
dc.subject4(3H)-Quinazolinonevi_VN
dc.subjectAcylhydrazonevi_VN
dc.subjectProcaspase-3vi_VN
dc.titleTổng hợp và thử hoạt tính gây độc tế bào ung thư của một số dẫn chất acylhydrazon mang khung 4(3H)-quinazolinonvi_VN
dc.typeArticlevi_VN
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