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https://dspace.ctu.edu.vn/jspui/handle/123456789/54649
Full metadata record
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Cao, Thị Cẩm Nhung | - |
dc.contributor.author | Lê, Công Trực | - |
dc.contributor.author | Cao, Việt Phương | - |
dc.contributor.author | Trần, Phương Thảo | - |
dc.contributor.author | Nguyễn, Hải Nam | - |
dc.date.accessioned | 2021-06-09T07:23:36Z | - |
dc.date.available | 2021-06-09T07:23:36Z | - |
dc.date.issued | 2018 | - |
dc.identifier.issn | 0866-7861 | - |
dc.identifier.uri | https://dspace.ctu.edu.vn/jspui/handle/123456789/54649 | - |
dc.description.abstract | 5 novel procaspase-3 activating acylhydrazones synthesized incorporating 4(3H)-quinazolinones (Va-ej and biologically tested for cytotoxicity. These all 5 synthesized compounds exhibited significant cytotoxicity against the foilwing three human cancer cell lines: SW620, colon cancer; PC-3, prostate cancer; NCI-H23, lung cancer. Of them, the most potent compound Vb displayed the highest cytotoxicity, as up to 4-fold as potent than 5-FU (5-fluorouracil). | vi_VN |
dc.language.iso | vi | vi_VN |
dc.relation.ispartofseries | Tạp chí Dược học;Số 510 .- Tr.3-7 | - |
dc.subject | 4(3H)-Quinazolinone | vi_VN |
dc.subject | Acylhydrazone | vi_VN |
dc.subject | Procaspase-3 | vi_VN |
dc.title | Tổng hợp và thử hoạt tính gây độc tế bào ung thư của một số dẫn chất acylhydrazon mang khung 4(3H)-quinazolinon | vi_VN |
dc.type | Article | vi_VN |
Appears in Collections: | Dược học |
Files in This Item:
File | Description | Size | Format | |
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_file_ Restricted Access | 3.87 MB | Adobe PDF | ||
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