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https://dspace.ctu.edu.vn/jspui/handle/123456789/54664
Title: | Bước đầu nghiên cứu bào chế viên hoàn giọt chứa đan sâm, tam thất trồng ở Việt Nam |
Authors: | Trần, Trọng Biên Nguyễn, Hà Yên Bùi, Thị Thúy Luyện Nguyễn, Văn Hân |
Keywords: | Danshen Salvia miltiorhiza Bunge and Panax notoginseng Burk Dripping pills Pill Danshensu |
Issue Date: | 2018 |
Series/Report no.: | Tạp chí Dược học;Số 510 .- Tr.43-48 |
Abstract: | Danshen dripping pills were formulated from the dry extracts of Salvia miltiorhiza Bunge and Panax notoginseng Burk, with PEG 6000 as carrier. The preparation was optimized as follows: Ratio of dry extract : PEG 6000 : bomeol- 1.0: 3.0 : 0.1; temperature of the melting mixture - 70-75°C; dropping rate -20 ±3 drops.min1; temperature of condensate parafin oil -(-5°C) - 0°C, condensation column length - 40 cm, dropping distance - 13 cm. The obtained dripping pills showed spherical shape with smooth surface, diameter of 3.69 mm, the roundness of 1.03, the disintegration time of 13-15 mins, the pill mean weight of 27.9 mg contaning 0.105 mg of danshensu. The obtained dripping pills proved to be new effective approach for pharmaceutical application. |
URI: | https://dspace.ctu.edu.vn/jspui/handle/123456789/54664 |
ISSN: | 0866-7861 |
Appears in Collections: | Dược học |
Files in This Item:
File | Description | Size | Format | |
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_file_ Restricted Access | 4.25 MB | Adobe PDF | ||
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