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Title: | Nghiên cứu điều chế cao lá chè xanh (Camellia sinensis (L.) Kuntze) giàu catechin sử dụng nhựa macroporous |
Authors: | Trần, Trọng Biên Nguyễn, Thị Phương Thảo Nguyễn, Văn Hân |
Keywords: | Catechin Enrichment Macroporous resin HPD826 EGCG |
Issue Date: | 2018 |
Series/Report no.: | Tạp chí Dược học;Số 510 .- Tr.58-61,71 |
Abstract: | In view that catechins account for anti-oxidative, anti-inflamatory, anti-tumor activity, the catechin-rich green tea extracts were prepared using macroporous resins. The obtained preparations were charaterized by various chemical and physical properties. Of the two tested resins, the H-bond resin HPD826 exhibited the better adsorption/desorption capability and desorption ratio to EGCG (as the main principal catechin of the green tea). The catechin enrichment was optimized by dynamic adsorption/desorption experiments on HPD826 resin columns. Under the optimized conditions, the EGCG content of the 30% ethanol eluents increased by 2.7-fold from 15.03% (in the cmde extracts) to 40.06%, with the recovery yield of approximately 70%. Experimentally, the macroporous resins made the preparation simple laid efficient ways for enlarging scale of enrichment catechin in natural products 6 the type for pharmaceutical application. |
URI: | https://dspace.ctu.edu.vn/jspui/handle/123456789/54672 |
ISSN: | 0866-7861 |
Appears in Collections: | Dược học |
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_file_ Restricted Access | 3.72 MB | Adobe PDF | ||
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