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https://dspace.ctu.edu.vn/jspui/handle/123456789/54679
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DC Field | Value | Language |
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dc.contributor.author | Nguyễn, Văn Hải | - |
dc.contributor.author | Nguyễn, Thị Thúy | - |
dc.contributor.author | Seyha, Kim | - |
dc.contributor.author | Sivmeiy, Chea | - |
dc.contributor.author | Đào, Nguyệt Sương Huyền | - |
dc.contributor.author | Nguyễn, Văn Giang | - |
dc.contributor.author | Nguyễn, Đình Luyện | - |
dc.date.accessioned | 2021-06-09T07:57:13Z | - |
dc.date.available | 2021-06-09T07:57:13Z | - |
dc.date.issued | 2018 | - |
dc.identifier.issn | 0866-7861 | - |
dc.identifier.uri | https://dspace.ctu.edu.vn/jspui/handle/123456789/54679 | - |
dc.description.abstract | Benzimidazole sulfonamides were synthesized by combination of two pharmacologically compatible moieties into a single molecule by attaching a sulfonamide moiety to a benzimidazole frame. Their structures are confirmed by 1H-NMR-spectroscopy and mass spectrometry. Of the 8 synthesized compounds, 7 (5a-7a, 4b-7b) were novel benzimidazole sulfonamides. The antibacterial activities of all the 8 synthesized compounds (4a-7a, 4b-7b) against standard strains of 5 Gram positive and 5 Gram negative bacteria were tested at 500 pg/mL by disk diffusion method. Of these, two sulfonamides (4a, 7b) showed promising antibacterial activity against both types of the tested bacteria. | vi_VN |
dc.language.iso | vi | vi_VN |
dc.relation.ispartofseries | Tạp chí Dược học;Số 510 .- Tr.72-74,81 | - |
dc.subject | Sulfonamide | vi_VN |
dc.subject | Benzimidazole | vi_VN |
dc.subject | Antibacterial | vi_VN |
dc.title | Nghiên cứu tổng hợp và thử hoạt tính kháng khuẩn một số dẫn chất Sulfonamid mới của benzimidazol | vi_VN |
dc.type | Article | vi_VN |
Appears in Collections: | Dược học |
Files in This Item:
File | Description | Size | Format | |
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_file_ Restricted Access | 3.32 MB | Adobe PDF | ||
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