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DC Field | Value | Language |
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dc.contributor.author | Phan, Đình Châu | - |
dc.contributor.author | Nguyễn, Văn Thịnh | - |
dc.contributor.author | Nguyễn, Tuấn Anh | - |
dc.contributor.author | Vũ, Bình Dương | - |
dc.date.accessioned | 2021-06-09T09:09:24Z | - |
dc.date.available | 2021-06-09T09:09:24Z | - |
dc.date.issued | 2018 | - |
dc.identifier.issn | 0866-7861 | - |
dc.identifier.uri | https://dspace.ctu.edu.vn/jspui/handle/123456789/54713 | - |
dc.description.abstract | To find a simple, effective way to synthesize amantadine and amantadine hydrochloride (1-aminoadamantane hydrochloride) for medicinal use as an antiviral in treatment of certain influenza infections (type A, for example), an antidyskinetic agent to treat Parkinson’s disease, as well, amantadine hydrochloride was synthesized from adamantane, nitric acid and acetonitrile via N-(1-adamantyl)-acetamide in two steps. The structure of the obtained amantadine hydrochloride was confirmed by IR, MS, ¹H-NMR, ¹³C-NMR. | vi_VN |
dc.language.iso | vi | vi_VN |
dc.relation.ispartofseries | Tạp chí Dược học;Số 512 .- Tr.14-17 | - |
dc.subject | Amantadine hydrochlonde | vi_VN |
dc.subject | Adamantane | vi_VN |
dc.subject | Nitric acid | vi_VN |
dc.subject | Acetonitrile | vi_VN |
dc.subject | N-(1-adamantyl)acetamide | vi_VN |
dc.subject | Antiviral | vi_VN |
dc.subject | Antidyskinetic agent | vi_VN |
dc.subject | Parkinson’s disease | vi_VN |
dc.title | Nghiên cứu về các dẫn chất của adamantan Phần VI: Phương pháp mới, đơn giản tổng hợp amantadin và amantadin hydroclorid sử dụng kỹ thuật chiếu xạ vi sóng | vi_VN |
dc.type | Article | vi_VN |
Appears in Collections: | Dược học |
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File | Description | Size | Format | |
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_file_ Restricted Access | 3.45 MB | Adobe PDF | ||
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