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Title: | Comparison of the SSSperm testing kit with the Halosperm testing kit in an analysis of sperm DNA fragmentation |
Authors: | Le, Thi Quyen Nguyen, Thi Minh Thu Le, Thi Minh Phuong Nguyen, Thi Trang |
Keywords: | Comparison DFI Improved test kit Infertile Sperm DNA fragmentation |
Issue Date: | 2020 |
Series/Report no.: | Vietnam Journal of Science, Technology and Engineering;Vol. 62, No. 02 .- P.71-76 |
Abstract: | The objectives of this work were to accurately evaluate testing kits that analyse sperm DNA fragmentation in infertile men and to provide a comparison of an improved testing kit (SSSperm testing kit) to the existing Halosperm testing kit in an analysis of sperm DNA fragmentation. A cross-sectional study was conducted on 300 semen samples from infertile men with a sperm concentration ≥1 million/ml using the Bland-Altman, T-test, and Pearson test for statistical study. The SSSperm testing kit had a coefficient of variation of CV% = 2.26% ≤ 5% and t tn=0.97 ≤ tc = 2. The two methods have similar DNA fragmentation index (DPI) results (r=0.995; p≤0.001). The difference between the results of the two kits was not statistically significant (p=0.236 ≥ 0.05). In conclusion, the SSSperm testing kit for the analysis of sperm DNA fragmentation is qualified as determined from quantitative tests, and the SSSperm testing kit is equivalent to the Halosperm testing kit. |
URI: | https://dspace.ctu.edu.vn/jspui/handle/123456789/71733 |
ISSN: | 2525-2461 |
Appears in Collections: | Vietnam journal of Science, Technology and Engineering |
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