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https://dspace.ctu.edu.vn/jspui/handle/123456789/9283
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DC Field | Value | Language |
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dc.contributor.author | Ho, My Dung | - |
dc.contributor.author | Vu, Thi Ngoc Thanh | - |
dc.contributor.author | Nguyen, Thi Thanh Ha | - |
dc.contributor.author | Nguyen, Thi Minh Hang | - |
dc.date.accessioned | 2019-06-18T02:09:00Z | - |
dc.date.available | 2019-06-18T02:09:00Z | - |
dc.date.issued | 2018 | - |
dc.identifier.issn | 2354-080X | - |
dc.identifier.uri | http://dspace.ctu.edu.vn/jspui/handle/123456789/9283 | - |
dc.description.abstract | To investigate the hypoglycemic action of CF2 in a type 2-like diabetic mice model induced by high fat diet (HFD) combined with streptozotocin (STZ) injection. Method: Model: mice were fed with HFD for 8 weeks, then injected with a dose of STZ (100 mg/kg body weight, intraperitoneal injection). Animal used: Swiss male mice. Drugs: type 2-like diabetic mice with HFD and STZ treated with either gliclazide 80 mg/kg body weight, CF2 2 m/kg or CF2 4 mg/kg body weight daily by oral route of ad-ministration during 14 days. Result: CF2 has blood glucose-lowering effect in type 2-like diabetic mice for 14 days treatment at doses of 2 mg/kg and 4mg/kg daily (p < 0.05). The blood glucose- lowering effect of CF2 at dose of 2 mg/kg daily is similar to gliclazide 80 mg/kg daily. CF2 at dose of 4mg/kg is more effective than that of 2 mg/kg and gliclazide 80 mg/kg in reducing blood glucose level. Conclusion: CF2 has effect on lowering blood glucose level at doses of 2 mg/kg and 4 mg/kg daily for 14 days in type 2-like diabetic mice, induced by HFD and STZ 100 mg/kg intraperitoneal injection. | vi_VN |
dc.language.iso | vi | vi_VN |
dc.relation.ispartofseries | Journal of Medical research;Vol.111E2(02) .- P.09-16 | - |
dc.subject | CF2 | vi_VN |
dc.subject | Callisia fragrans | vi_VN |
dc.subject | Ecdysteroid | vi_VN |
dc.subject | Tye 2-like diabetic mice | vi_VN |
dc.subject | STZ | vi_VN |
dc.subject | HFD | vi_VN |
dc.subject | Blood glucose | vi_VN |
dc.title | Study on the hypoglycemic action of CF2 in induced type 2-like diabetic mice model | vi_VN |
dc.type | Article | vi_VN |
Appears in Collections: | Nghiên cứu y học (Journal of Medical Research) |
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