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  3. Vietnam Journal of Chemistry
Please use this identifier to cite or link to this item: https://dspace.ctu.edu.vn/jspui/handle/123456789/22198
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dc.contributor.authorTran, Van Chien-
dc.contributor.authorNguyen, The Anh-
dc.contributor.authorTran, Thi Phuong Thao-
dc.contributor.authorLe, Dac Phuong-
dc.contributor.authorPham, Thi Tham-
dc.contributor.authorNguyen, Quang Tung-
dc.contributor.authorTran, Van Loc-
dc.date.accessioned2020-03-06T07:31:24Z-
dc.date.available2020-03-06T07:31:24Z-
dc.date.issued2019-
dc.identifier.issn2525-2321-
dc.identifier.urihttp://dspace.ctu.edu.vn/jspui/handle/123456789/22198-
dc.description.abstractThe synthesis of valsartan (1), one of the most currently used pharmaceutical agent in antihypertensive therapy, was described through five steps in an overall yield of 54 % starting from 4’-methyl-2-cyanobiphenyl (2). The key step involved tetrazole ring formation catalyzed by Lewis acid. The structures of synthesized compounds were confirmed by means of NMR and MS spectroscopie.vi_VN
dc.language.isoenvi_VN
dc.relation.ispartofseriesVietnam Journal of Chemistry;No 57(03) .- Page.343-346-
dc.subjectValsartanvi_VN
dc.subjectAntihypertensionvi_VN
dc.subjectBiphenyltetrazolevi_VN
dc.subjectLewis acidvi_VN
dc.titleSynthesis of Valsartan as drug for the treatment of hypertensionvi_VN
dc.typeArticlevi_VN
Appears in Collections:Vietnam Journal of Chemistry

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