Please use this identifier to cite or link to this item: https://dspace.ctu.edu.vn/jspui/handle/123456789/23343
Title: Antiproliferative activity of isolated compounds from Pinus dalatensis and Pinus krempfii on acute myeloid Leukemia cells
Authors: Nguyen, Hoang Sa
Nguyen, Thanh Tam
Tran, Duc Quan
Nguyen, Thi Hoang Anh
Nguyen, Thi Thuy Linh
Le, Thi Hong Nhung
Adorisio Sahrina
Delfino, Domenico V
Tran, Van Sung
Trinh, Thi Thuy
Keywords: Pinus dalatensis
Pinus krempfìi
Chrysin
Acute mycloid leukemia (OCI-ALM)
Issue Date: 2019
Series/Report no.: Vietnam Journal of Chemistry;№ 57(04) .- Page.520-523
Abstract: Our previous chemical constituent study of Pinuts dalatensis and Pinus krempfìi had identified six compounds 1-6. The continuing investigation of biological activity of the conifer species led to discovery of the antiproliferative activity of all isolated compounds 1-6 on acute myeloid leukemia cells as shown by the effects on cell cycle progression. Re-markably, compound 3 (chrysin) exibited potent bioactivity at the concentration of 10 µg-mL.
URI: http://dspace.ctu.edu.vn/jspui/handle/123456789/23343
ISSN: 2525-2321
Appears in Collections:Vietnam Journal of Chemistry

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