Please use this identifier to cite or link to this item: https://dspace.ctu.edu.vn/jspui/handle/123456789/2626
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dc.contributor.authorBùi, Thị Bửu Huê-
dc.contributor.authorVõ, Đức Duy-
dc.contributor.authorTrương, Văn Kiệt-
dc.contributor.authorTú, Thị Kim Cúc-
dc.contributor.authorChâu, Nguyên Trâm Yên-
dc.contributor.authorMai, Văn Hiếu-
dc.date.accessioned2018-07-02T07:18:11Z-
dc.date.available2018-07-02T07:18:11Z-
dc.date.issued2015-
dc.identifier.issn0039-7911-
dc.identifier.urihttp://172.18.63.105/jspui/handle/123456789/2626-
dc.description.abstractA facile synthetic method for the construction of 2-substituted-4-oxo-4H-quinolizine-based core structure has been successfully developed. The synthesis made use of a one-pot Stobbe condensation followed by cyclization starting from the commercially available 2-pyridinecarbaldehyde. The structure of the formed 4-oxo-4H-quinolizine-2-carboxylate was fully confirmed by mass spectra, 1H NMR and 13C NMR, correlation spectrography, heteronuclear multiple bond correlation, and heteronuclear single quantum coherence (HSQC) spectra. The ethyl carboxylate moiety was then further functionalized via direct aminolysis by a range of amines to afford the corresponding 4-oxo-4H-quinolizine-2-carboxamides 4a–i in moderate to good yields.vi_VN
dc.language.isoenvi_VN
dc.relation.ispartofseriesSynthetic Communications;10.1080/00397911.2015.1112918-
dc.subject4-oxo-4H-quinolizinevi_VN
dc.subjectCarboxamidevi_VN
dc.subjectStobbe condensationvi_VN
dc.titleFacile Synthesis of 4-Oxo-4H-Quinolizine-2-carboxamide Derivativesvi_VN
dc.typeArticlevi_VN
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