Please use this identifier to cite or link to this item: https://dspace.ctu.edu.vn/jspui/handle/123456789/54621
Title: Tổng hợp và thử tác dụng ức chế enzym glutaminyl cyclase của một số dẫn chất N-(4-methoxy-3-aminoalkyloxy- phenyl) thiourea mói
Authors: Trần, Phương Thảo
Hoàng, Văn Hải
Keywords: N-(4-Methoxy-3-aminoalkyloxy-phenyl)thiourea
Thiourea
Inhibition
Glutaminyl cyclase
Issue Date: 2018
Series/Report no.: Tạp chí Dược học;Số 509 .- Tr.33-36,87
Abstract: A new series of N-(4-methoxy-3-aminoalkyloxy-phenyl)thiourea were synthesized and their glutaminyl cyclase (QC) inhibitivity was fluorometrically evaluated The compounds were obtained via 6 or 7 steps by well-known reactions. Of these synthesized compounds, four (22-25) showed potential inhibitory activity on glutaminyl cyclase (QC) (ICX values of 9,026.8 nM).
URI: https://dspace.ctu.edu.vn/jspui/handle/123456789/54621
ISSN: 0866-7861
Appears in Collections:Dược học

Files in This Item:
File Description SizeFormat 
_file_
  Restricted Access
3.83 MBAdobe PDF
Your IP: 3.238.125.76


Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.