Please use this identifier to cite or link to this item: https://dspace.ctu.edu.vn/jspui/handle/123456789/63827
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dc.contributor.authorNguyen, Phuc Dam-
dc.contributor.authorVo, Minh Dien-
dc.contributor.authorLuong, Huynh Vu Thanh-
dc.contributor.authorPham, Thi Thanh Hien-
dc.contributor.authorNguyen, Thi Thu Tram-
dc.date.accessioned2021-09-09T02:23:03Z-
dc.date.available2021-09-09T02:23:03Z-
dc.date.issued2019-
dc.identifier.issn2525-2518-
dc.identifier.urihttps://dspace.ctu.edu.vn/jspui/handle/123456789/63827-
dc.description.abstractThe antimicrobial potential of the four extracts of Momordica charantia L. var. abbreviata Ser., including hexane, chloroform, ethyl acetate and methanol-water 80:20 (v/v) extracts was screened against four bacterial and four fungal strains, using microbroth dilution assay. The chloroform extract showed the highest growth inhibitory activity with MIC = 200 μg/mL on both Escherichia coli and Bacillus subtilis and MIC = 100 μg/mL on Aspergillus niger. Phytochemical study on the bioactive chloroform extract led to the isolation of four known compounds as octadecan-1-ol (1), (23E)-5β,19-epoxycucurbita-6,23,25-trien-3β-ol (2), 5α-poriferasta-7,25-dien-3β-ol (3) and 3-O-(6'-O-palmitoyl-β-D-glucopyranosyl)-clerosterol (4). Their structures were elucidated by spectroscopic methods including 1D- and 2D-NMR, MS and in comparison with literature data. Here, such metabolites were reported for the first time from M. charantia L. var. abbreviata Ser.vi_VN
dc.language.isoenvi_VN
dc.relation.ispartofseriesVietnam Journal of Science and Technology;Vol. 57, No. 02 .- P.155–161-
dc.subject5α-poriferasta-7,25-dien-3β-olvi_VN
dc.subjectAntibacterialvi_VN
dc.subjectAntifungalvi_VN
dc.subjectClerosterolvi_VN
dc.subjectMomordica charantia L. var. abbreviata Servi_VN
dc.titleInvestigation of antimicrobial activity and chemical constituents of momordica charantia L.Var.Abbreviata Ser.vi_VN
dc.typeArticlevi_VN
Appears in Collections:Vietnam journal of science and technology

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