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Title: Identification of CYP2C9, VKORC1 genotypes and recommendation of warfarin dose for Vietnamese cardiovascular patients
Authors: Nguyen, Dang Ton
Nguyen, Thị Thanh Hoa
Nguyen, Phan Anh
Vu, Phuong Nhung
Le, Thi Bich Thao
Nguyen, Hai Ha
Keywords: Warfarin
CYP2C9 gene
VKORC1 gene
Issue Date: 2019
Series/Report no.: Journal of Biotechnology;№ 17(04) .- Page.589-594
Abstract: Warfarin is a well-known anticoagulant that capable of reducing the activity of vitamin K-dependent clotting factors. lt has been widely used for cardiovascular patients. However, patient's genotypes of CYP2C9 and VKORC1 remarkably affects the metabolism of warfarin. This study aims to identily the CYP2C9 and VKORC1 genotypes of 96 Vietnamese patients suffering cardiodynia or myocardial infarction and establish their daily warfarin dose.
ISSN: 1811-4989
Appears in Collections:Công nghệ sinh học

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