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Title: Effect of fluoxetine on the inhibition of adenylate cyclase activity in foskolin-stimulated mltc-1 leydig cells
Authors: Nguyen, Thi Mong Diep
Nguyen, Thi Bich Hang
Nguyen, Le Cong Minh
Tran, Thanh Son
Nguyen, Thuy Duong
Keywords: AMPK
Cyclic adenosine monophosphate
MLTC-1 cells
Issue Date: 2019
Series/Report no.: Journal of Biotechnology;№ 17(04) .- Page.595-602
Abstract: Fluoxetine (FLX), a widely used antidepressant primarily acting as a selective serotonin reuptake inhibitor, has bccn shown to exhibit other mechanisms oi' action in various cell types. Cyclic adenosine monophosphate (cAMP) is a second messenger used for intracellular signal induction. Cyclic AMP is a nucleotide synthesized within the cell from adenosine triphosphate by the adenylyl cyclase enzyme, and is inactivated enzymatically to 5'AMP by hydroxylation with a group of enzymes called phosphodiesterase.
ISSN: 1811-4989
Appears in Collections:Công nghệ sinh học

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