Please use this identifier to cite or link to this item: https://dspace.ctu.edu.vn/jspui/handle/123456789/41284
Title: Lignans from leaves of Amesiodendron chinense and their cytotoxic activity
Authors: Ho, Van Ban
Trinh, Thi Thanh Van
Vu, Van Chien
Nguyen, Thi Hue
Pham, Thi Hang
Nguyen, Le Tuan
Nguyen, Xuan Nhiem
Pham, Van Cuong
Nguyen, Quoc Vuong
Keywords: Amesiodendron chinense
Cytotoxic activity
Lignans
Issue Date: 2020
Series/Report no.: Vietnam Journal of Science and Technology;Vol. 58, No. 04 .- P.442-449
Abstract: Four lignans, (+)-aptosimon (1), (+)-isolariciresinol (2), (-)-cleomiscosin A (3), and (-)-cleomiscosin C (4) were isolated from the leaves of Amesiodendron chinense (Mer.) Hu. Their chemical structures were determined by spectroscopic analysis including MS, 1D and 2D NMR as well as by comparison with reported literatures. All compounds were evaluated for cytotoxic activity against five human cancer cell lines, KB, SK-LU-1, MCF-7, HepG-2, and SW-480. The compounds showed weak cytotoxic activity with IC50 values ranging from 32.61 to 95.18 µg/mL.
URI: https://dspace.ctu.edu.vn/jspui/handle/123456789/41284
ISSN: 2525-2518
Appears in Collections:Vietnam journal of science and technology

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